Blood Sugar Levels and Cataract in Alloxan-Treated, Galactose-Fed and Xylose-Fed Weanling Rats.

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Abstract
Cataract was produced experimentally in weanling littermate rats by (1) alloxan treatment, (2) galactose feeding, and (3) xylose feeding. All groups showed greatly elevated blood sugar levels as compared with untreated controls receiving glucose. Cataract was exhibited by all of the xylose- and galac-tose-fed rats, and by nearly all of the alloxan-treated rats. However, the development of cataract was much slower in the alloxan-treated than in the other groups. It is concluded that not only the level of blood sugar, but also the specific configuration of the sugar concerned is a factor in its cataractogenic action.

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