Specificity of Fowl and Mammalian Antigonadotropic Sera.

Abstract
Sheep antigonadotropic rabbit serum, aspecific in nature, although effective in inhibiting the gonadotropic action of extracts of mammalian tissues and fluids did not prevent the typical effect of gonadotropic extracts made from chicken hypophyses. Chicken antigonadotropic rabbit serum, while inhibiting the gonadotropic action of chicken pituitary glands, was ineffective against gonadotropic extracts of sheep pituitary glands. The possible relationship of these experiments are discussed in regard to the nature of the antihormone mechanism.

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