Novel Mechanism of Inhibition of HIV-1 Reverse Transcriptase by a New Non-nucleoside Analog, KM-1

This publication has 34 references indexed in Scilit:

• Molecular Mechanisms of Tenofovir Resistance Conferred by Human Immunodeficiency Virus Type 1 Reverse Transcriptase Containing a Diserine Insertion after Residue 69 and Multiple Thymidine Analog-Associated Mutations
  Antimicrobial Agents and Chemotherapy, 2004
• Toxicity of Nucleoside Analogues Used to Treat AIDS and the Selectivity of the Mitochondrial DNA Polymerase
  Biochemistry, 2003
• Update on HIV resistance and resistance testing
  Medicinal Research Reviews, 2003
• A Tight-Binding Mode of Inhibition Is Essential for Anti-Human Immunodeficiency Virus Type 1 Virucidal Activity of Nonnucleoside Reverse Transcriptase Inhibitors
  Antimicrobial Agents and Chemotherapy, 2002
• The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1
  Journal of Virology, 2002
• Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors 1 1Edited by J. Karn
  Journal of Molecular Biology, 2001
• Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase 1 1Edited By J.Karn
  Journal of Molecular Biology, 1998
• Analysis of HIV-2 RT mutants provides evidence that resistance of HIV-1 RT and HIV-2 RT to nucleoside analogs involves a repositioning of the template-primer
  Journal of Molecular Biology, 1997
• Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors
  Nature Structural & Molecular Biology, 1995
• HIV‐1‐specific RT inhibitors: Highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase
  Medicinal Research Reviews, 1993