Antiserum to lens antigens immunostains Müller glia cells in the neural retina.
- 1 August 1985
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 82 (16) , 5570-5573
- https://doi.org/10.1073/pnas.82.16.5570
Abstract
Antiserum to a lens fraction enriched for alpha-crystallin selectively immunostains Müller glia cells in the neural retina of several vertebrate species. Also, in embryonic retina (chicken), this antiserum reacts with Müller cells and, at early stages of development, with their apparent precursors. Thus, antibodies to a lens product(s) detect a Müller glia cell marker that begins to be expressed very early in their ontogeny and can be useful in studies on differentiation, function, and pathologies of this cell type.This publication has 15 references indexed in Scilit:
- Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.Proceedings of the National Academy of Sciences, 1982
- Carbonic anhydrase C in the neural retina: transition from generalized to glia-specific cell localization during embryonic development.Proceedings of the National Academy of Sciences, 1981
- Lens Differentiation in VertebratesDifferentiation, 1981
- Lentoids in aggregates of embryonic neural retina cellsCell Differentiation, 1981
- Cellular metaplasia or transdifferentiation as a model for retinal cell differentiation.1980
- Induction of glutamine synthetase in embryonic neural retina: localization in Müller fibers and dependence on cell interactions.Proceedings of the National Academy of Sciences, 1979
- Sequence complexity and tissue distribution of chick lens crystallin mRNAsDevelopmental Biology, 1978
- Biochemical and immunological studies of lentoid formation in cultures of embryonic chick neural retina and day-old chick lens epitheliumDevelopmental Biology, 1977
- Selective reassociation of the crystallinsExperimental Eye Research, 1975
- Formation of Lentoids by Dissociated Retinal Cells of the Chick EmbryoScience, 1957