This is a report of two fairly well substantiated cases of subacute leukemia in which follow-up studies and careful clinical observation during the course of the disease failed to provide a clear-cut diagnosis until the terminal state. The bone marrow findings were apparently normal even though the clinical condition was serious. It was only terminally that the bone marrow revealed the classical findings of leukemia. The problem these two cases present has been noted in all parts of the world and more instances are being reported.