Immunoreactive β-Endorphin, Cortisol, and Growth Hormone Plasma Levels in Obsessive-Compulsive Disorder

Abstract
Summary Basal morning plasma levels of immunoreactive-β-endorphin (ir-β-EP), cortisol, and growth hormone (GH) were assessed in 13 obsessive-compulsive disorder (OCD) patients in comparison to 20 healthy controls. All subjects were drug free for at least 1 year. The mean plasma level of ir-β-EP was significantly lower (36%) in the OCD patients when compared with the control subjects. The decrease in ir-β-EP was not accompanied by alteration in cortisol and GH plasma levels.

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