Molecular and clinical characteristics of respiratory syncytial virus infections in hospitalized children
- 14 January 2004
- journal article
- Published by Springer Nature in Medical Microbiology and Immunology
- Vol. 194 (1-2) , 67-71
- https://doi.org/10.1007/s00430-003-0215-9
Abstract
The objective of this study was to determine the importance of respiratory syncytial virus (RSV) for hospitalization in the north east of Germany and to obtain molecular epidemiological data of the circulating strains. Using a rapid and sensitive reverse transcriptase-PCR, it was found that a quarter of pediatric respiratory disease admissions were due to RSV. Infections caused by RSV in hospitalized patients were determined over the whole year. Both RSV groups A and B were identified with a predominance of RSV A (86%) over the entire period. The analysis of the deduced amino acid sequences by direct sequencing showed that very similar RSV strains are circulating in the community.Keywords
This publication has 22 references indexed in Scilit:
- Real-time PCR to improve the diagnosis of respiratory syncytial virus infectionJournal of Medical Microbiology, 2003
- Simultaneous Detection, Subgrouping, and Quantitation of Respiratory Syncytial Virus A and B by Real-Time PCRJournal of Clinical Microbiology, 2003
- Reliable Detection of Respiratory Syncytial Virus Infection in Children for Adequate Hospital Infection Control ManagementJournal of Clinical Microbiology, 2001
- Molecular Epidemiology of Outbreak of Respiratory Syncytial Virus within Bone Marrow Transplantation UnitJournal of Clinical Microbiology, 2001
- Nosocomial respiratory syncytial virus infections in children’s wardsDiagnostic Microbiology and Infectious Disease, 2000
- Respiratory Syncytial Virus Infection in AdultsClinical Microbiology Reviews, 2000
- Circulation Patterns of Group A and B Human Respiratory Syncytial Virus Genotypes in 5 Communities in North AmericaThe Journal of Infectious Diseases, 2000
- Recent progress in antiviral chemotherapy for respiratory syncytial virus infectionsExpert Opinion on Investigational Drugs, 2000
- International variation in the management of infants hospitalized with respiratory syncytial virusEuropean Journal of Pediatrics, 1998
- Analysis of relatedness of subgroup A respiratory syncytial viruses isolated worldwideVirus Research, 1992