Activity of Derivatives and Analogs of Dapsone Against Mycobacterium leprae
- 1 November 1978
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 14 (5) , 791-793
- https://doi.org/10.1128/aac.14.5.791
Abstract
Of 25 dapsone derivatives and analogs screened for activity against Mycobacterium leprae in the mouse footpad system, only 7 were active. All seven were metabolized to or contaminated with dapsone.This publication has 15 references indexed in Scilit:
- The Action of Dapsone on a Susceptible Strain ofMycobacterium kansasiiLeprosy Review, 1978
- Disposition of the Antileprosy Drug, Dapsone, in the MouseExperimental Biology and Medicine, 1972
- Application of Spectrophotofluorometric Procedures to Some Problems in Mycobacterium Leprae Infections in Mice and Man Treated with Dapsone (DDS), Diacetyl-DDS (DADDS), and Di-Formyl-DDS (DFD)The American Journal of Tropical Medicine and Hygiene, 1971
- The Minimal Inhibitory Concentrations of Sulphadimethozine and Sulphadoxine AgainstMycobacterium lepraeLeprosy Review, 1970
- Further experience with the kinetic method for the study of drugs against Mycobacterium leprae in mice. Activities of DDS, DFD, ethionamide, capreomycin and PAM 1392.1969
- A method for counting acid-fast bacteria.1968
- Activity of Repository Sulfones Against Mycobacterium leprae In Mice.Experimental Biology and Medicine, 1967
- Antimicrobial Therapy of Experimental Human Leprosy (Myco. leprae) Infection in the Mouse Foot PadLeprosy Review, 1967
- ABSORPTION, METABOLISM AND EXCRETION OF DI(p‐AMINOPHENYL) SULPHONE (DAPSONE) AND DI(p‐AMINOPHENYL) SULPHOXIDE IN MANBritish Journal of Pharmacology and Chemotherapy, 1966
- THE IN VIRTO ACTIVITY OF 4,4'-DIAMINODIPHENYL SULFONE AGAINST VARIOUS ACID-FAST MICROORGANISMS.1963