Rapid Accumulation of Eosinophils in Lung Lesions in Guinea Pigs Infected with Mycobacterium tuberculosis
Open Access
- 1 February 2004
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 72 (2) , 1147-1149
- https://doi.org/10.1128/iai.72.2.1147-1149.2004
Abstract
Guinea pig eosinophils were positively identified in bronchoalveolar lavage populations and in the lung granulomas of Mycobacterium tuberculosis -infected guinea pigs. It is possible that the rapid influx of these cells, and their subsequent degranulation during acute pulmonary tuberculosis, may play a key role in the susceptibility of this animal model.Keywords
This publication has 13 references indexed in Scilit:
- Granuloma Formation in Mouse and Guinea Pig Models of Experimental TuberculosisPublished by American Society for Microbiology ,2014
- Guinea Pig Model of TuberculosisPublished by American Society for Microbiology ,2014
- Immunopathogenesis of Pulmonary Granulomas in the Guinea Pig after Infection withMycobacterium tuberculosisInfection and Immunity, 2003
- Human Eosinophil Peroxidase Induces Surface Alteration, Killing, and Lysis ofMycobacterium tuberculosisInfection and Immunity, 2003
- Neutrophil-Mediated Mycobacteriocidal Immunity in the Lung duringMycobacterium bovisBCG Infection in C57BL/6 MiceInfection and Immunity, 2002
- Inflammation and Lymphocyte Activation during Mycobacterial Infection in the Interferon-γ-Deficient MouseCellular Immunology, 2001
- Neutrophils Play a Protective Nonphagocytic Role in SystemicMycobacterium tuberculosisInfection of MiceInfection and Immunity, 2000
- Eosinophils: Biology and Role in DiseasePublished by Elsevier ,1995
- Pulmonary Eosinophilia in Pulmonary TuberculosisChest, 1992
- Delayed-type hypersensitivity and cell-mediated immunity in the pathogenesis of tuberculosisImmunology Today, 1991