Morphine dependent behaviour in rats: some clinical implications
- 1 May 1973
- journal article
- research article
- Published by Cambridge University Press (CUP) in Psychological Medicine
- Vol. 3 (2) , 225-237
- https://doi.org/10.1017/s0033291700048571
Abstract
Synopsis An animal model of morphine dependence is described, in which rats learned to overcome their aversion to solutions of morphine and eventually drank such solutions in preference to water on choice trials. Selected aspects of the acquisition, maintenance, and elimination of this type of morphine dependent behaviour were studied and the findings are discussed in terms of their relevance to man.Keywords
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