Synthesis of Novel Quinoline Quinols and Isoquinoline Quinols from Quinones
- 1 January 1985
- journal article
- research article
- Published by CLOCKSS Archive in HETEROCYCLES
- Vol. 23 (2) , 387-390
- https://doi.org/10.3987/r-1985-02-0387
Abstract
Quinoline quinols and isoquinoline quinols [which have a number of biological activities] were synthesized from the corresponding quinoline quinones and isoquinoline quinones, respectively, by the series of reactions, protection of 1 carbonyl with trimethylsilyl cyanide, reaction with methyl lithium or the enolate of methyl acetate, and hydrolytic deprotection with aqueous silver fluoride.Keywords
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