The Lack of Utility of Circulating Biomarkers of Inflammation and Endothelial Dysfunction for Type 2 Diabetes Risk Prediction Among Postmenopausal Women

Open Access
Publisher Website
Google Scholar
Abstract
Type 2 diabetes mellitus (DM) is a leading cause of morbidity and mortality in the United States.1 According to the Centers for Disease Control and Prevention, more than 24 million Americans were living with diabetes in 2007,2 and this number is forecasted to increase to 48 million by 2050.3 The alarming surge of diabetes incidence highlights the importance of developing effective screening and preventive measures to control this devastating disease. Among high-risk individuals, lifestyle modification and pharmacological interventions have been demonstrated to be effective.4,5 It is therefore of clinical and public health importance to identify high-risk individuals for aggressive treatment.