The synthesis and biological activity of the marine metabolite cylindrospermopsin

Abstract
The marine natural product cylindrospermopsin has attracted much attention due to its high toxicity, its widespread occurrence in the environment and its complex chemical structure. This article discusses the isolation and structure determination of cylindrospermopsin, together with its impact on the environment and also covers the diverse synthetic methodologies which are currently under investigation directed towards the total synthesis of this intriguing molecule.

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