Heavy Chain Disease of the µ (γM) Type: Report of the First Case
Open Access
- 1 August 1970
- journal article
- Published by American Society of Hematology in Blood
- Vol. 36 (2) , 137-144
- https://doi.org/10.1182/blood.v36.2.137.137
Abstract
The serum of a patient with chronic lymphocytic leukemia, and amyloidosis, was found to contain an unusual protein with µ chain antigenic determinants. It was devoid of light chains and was present in the form of multiple disulfide linked polymers. The patient also had a kappa Bence Jones protein in the serum and urine. The possibility is raised that the heavy chain lacks a portion of the chain necessary for coupling with light chains.Keywords
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