Natural killer cell activity during measles
Open Access
- 1 August 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical and Experimental Immunology
- Vol. 81 (2) , 218-224
- https://doi.org/10.1111/j.1365-2249.1990.tb03321.x
Abstract
Natural killer cells are postulated to play an important role in host anti‐viral defences. We measured natural killer cell activity in 30 individuals with acute measles (73 ± 21 lytic units (LU)/107 cells) and 16 individuals with other infectious diseases (149 ± 95 LU) and found it reduced compared with values for adults (375 ± 70 LU; PPin vitro exposure of cells to interleukin‐2. Depressed natural killer cell activity parallels in time the suppression of other parameters of cell‐mediated immunity that occurs during measles.Keywords
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