QA-2 AND QA-3 ANTIGENS ON LYMPHOCYTE SUB-POPULATIONS .1. MITOGEN RESPONSIVENESS

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 121  (5) , 1640-1643
Abstract
The effects of anti-Qa-2 plus C [complement] and anti-Qa-3 plus C on mitogen-induced proliferation were studied [using mouse lymphocytes]. Both of these antisera in the presence of C markedly reduced both Con [concanavalin] A- and PHA[phytohemagglutinin]-induced proliferation while having little or no effect on LPS[lipopolysaccharide]-induced proliferation. LPS, Con A and PHA cultures and cultures containing media alone, examined at 72 h, contained high proportions of Qa-2+ and Qa-3+ cells.