Feto-Maternal Bleeding:During Pregnancy and at Delivery

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Abstract
Blood samples from pregnant women and from mothers before and after delivery were tested for the occurrence of feto-maternal bleeding (fmb) using Kleihauers acid-elution technique and a counting technique described by Schneider. It was assumed that fmb had occurred when there was a clinically significant difference between the values of Hb-F [fetal hemoglobin] cells/million cells in 2 blood samples. Fmb occurred in nearly 2/3 of the mothers after pregnancy and delivery. The fmb were most often less than 0.1 ml, and only a few percent had fmb between 0.1-1 ml. Abortion, complicated pregnancies, amniocentesis, pre-eclampsia, cesarean section and other types of complicated deliveries increased the risk of larger fmb.

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