THE RELATIONSHIPS OF VIRAL CONTENT OF LIVING AND DEAD WHOLE EGGS INOCULATED WITH VARIOUS CONCENTRATIONS OF PSITTACOSIS VIRUS

Publisher Website
Google Scholar
Abstract
Psittacosis virus, Borg strain, was inoculated into 8 day embryonated eggs at concns. of 50,000, 5000, 500, and 50 LD50 doses per ml. The temp, of incubation was 37.5[degree]C Selective lot samples of dead and living eggs were ground in the Waring blendor and intracerebral mouse assays of the virus content determined. Growth curves were detd. biometrically using linear regressions. From this analysis several facts became evident: (1) the greater the viral concn. in the inoculum the less viral return through multiplication because of early high death rate; and (2), conversely, those eggs inoculated with the lower concn. of inoculum had a lower death rate and a greater time for viral propagation and hence yielded a greater concn. per unit of inoculum.

This publication has 1 reference indexed in Scilit: