Effect of Ovariectomy on the Oxidative Activity of the Hypothalamus and of the Limbic System of the Rat

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Abstract
The oxidative activity was determined in the hypothalamus, amygdala, and hippocampus of intact and ovariectomized rats. Following castration, the hypothalamic metabolism was depressed to levels below the diestrus values of the intact rats. The amygdala andhippocampus, on the other hand, presented a sustained high value of oxygen uptake. This is in contrast with the pattern normally seen in the various phases of the estrous cycle, where the QO2 of the amygdala is at its highest value during estrus, while hippocampal QO2 reaches its maximum during diestrus.

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