Two Cases of Fatal Intoxication due to Tranylcypromine Overdose
- 1 January 1991
- journal article
- case report
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 15 (1) , 38-40
- https://doi.org/10.1093/jat/15.1.38
Abstract
Two cases of death following the ingestion of tranylcypromine are presented. High concentrations of tranylcypromine were determined in blood, urine, and liver by gas-liquid chromatography. Tranylcypromine was extracted from buffered blood with n-butyl chloride. The evaporated extract was derivatized with trifluoroacetic anhydride and analyzed by gas chromatography with nitrogen-phosphorus selective detection. The method was linear in blood over the range 0.5–20 mg/L with a limit of quantitation of about 0.2 mg/L.Keywords
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