Region of Difference 1 in Nontuberculous Mycobacterium Species Adds a Phylogenetic and Taxonomical Character

15 September 2009

journal article
research article
Published by American Society for Microbiology in Journal of Bacteriology

Vol. 191 (18) , 5865-5867
https://doi.org/10.1128/jb.00683-09

Abstract

The esat-6 and cfp-10 genes are essential for virulence in Mycobacterium tuberculosis. Among nontuberculous mycobacteria, we found these genes only in M. kansasii, M. szulgai, M. marinum, and M. riyadhense, with unique sequences. This adds a phylogenetic and taxonomical characteristic and may represent a virulence factor for nontuberculous mycobacteria.

Keywords

This publication has 18 references indexed in Scilit:

Clinical Relevance ofMycobacterium szulgaiin The Netherlands
Clinical Infectious Diseases, 2008
M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
Cell, 2007
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
Molecular Biology and Evolution, 2007
An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases
American Journal of Respiratory and Critical Care Medicine, 2007
ESAT‐6 and CFP‐10 in Clinical versus Environmental Isolates ofMycobacterium kansasii
The Journal of Infectious Diseases, 2005
A multigene approach to phylogenetic analysis using the genus Mycobacterium as a model
International Journal of Systematic and Evolutionary Microbiology, 2005
Interferon-γ assays in the immunodiagnosis of tuberculosis: a systematic review
The Lancet Infectious Diseases, 2004
Genomic Interrogation of the Dassie Bacillus Reveals It as a Unique RD1 Mutant within the Mycobacterium tuberculosis Complex
Journal of Bacteriology, 2004
Deletion of RD1 fromMycobacterium tuberculosisMimics Bacille Calmette‐Guérin Attenuation
The Journal of Infectious Diseases, 2003
A Mycobacterium tuberculosis operon encoding ESAT=6 and a novel low-molecular-mass culture filtrate protein (CFP-10)
Microbiology, 1998