Plus and Minus Single-Stranded DNA Separately Encapsidated in Adeno-Associated Satellite Virions
- 5 December 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3910) , 1280-1282
- https://doi.org/10.1126/science.166.3910.1280
Abstract
Based on physical and chemical determinations, the mnolecular weight of the type 4 adeno-satellite virus is 5.4 X 106 daltons, and the virion contains 1.4 X 106 daltons of DNA. Denaturation and renaturation studies indicate that the viral genome is a single-stranded DNA molecule and that each virion contains either a minus or a plus strand. Upon extraction, the minus and plus strands unite to form double-stranded DNA molecules with no obvious excess of unpaired strands.Keywords
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