Allomorphic Forms of Bacteriophage φX-174 Replicative DNA
- 4 November 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 154 (3749) , 658-660
- https://doi.org/10.1126/science.154.3749.658
Abstract
The bacteriophage øX-174 replicative form of DNA exists in two configurations, as judged by electron microscopy and sucrose density gradient sedimentation, and on methylated albumin-coated kieselguhr column chromatography.The predominant 21S form of the DNA is a tightly twisted circle. Treatment with deoxyribonuclease causes a single scission in one of the two strands, resulting in an open circle which sediments at 16S.This publication has 7 references indexed in Scilit:
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