Fecal and Oral Shedding of Helicobacter pylori From Healthy Infected Adults

Abstract
Helicobacter pylori causes peptic ulcers and has been implicated in the etiology of distal gastric cancer.1 However, it is not known how H pylori is transmitted. This uncertainty stems from 4 unresolved questions: (1) how does the organism leave its host and enter the environment? (2) where in the environment does the organism reside? (3) when do people acquire infection? and (4) are all people susceptible to infection? While most epidemiological evidence supports direct person-to-person transmission, the manner in which this occurs is unknown.2-4