CORTISONE TREATMENT OF SUBACUTE NONSUPPURATIVE THYROIDITIS: REPORT OF TWO CASES

Abstract
One case of acute and another of subacute nonsuppurative thyroiditis are reported in which prompt relief of symptoms and cure within a wk. followed the admn. of 100 mg. cortisone daily, intramusc., in the 1st case, and 150 mg. daily by mouth, in the 2d case. Both patients had failed to respond to prior courses of antibiotics and one had had a prompt recrudescence after a standard course of roentgen therapy. The pathologic and clinical characteristics of this entity are summarized. Other cases recently reported in the literature are mentioned. It was felt that, despite the prompt and definitive cessation of symptoms and signs in these cases, some cases would probably require longer treatment or repetitions of the initial course of treatment. It was further suggested that the alleviation of the disease was a function of the anti-inflammatory action or cortisone rather than its hormonal influence on the thyroid.

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