Clinical Trial with Nimesulide, a New Non-Steroid Anti-Inflammatory Agent, in Rheumatic Pathology
- 1 September 1981
- journal article
- research article
- Published by SAGE Publications in Journal of International Medical Research
- Vol. 9 (5) , 349-352
- https://doi.org/10.1177/030006058100900509
Abstract
The author reports the use of a new non-steroid drug, endowed with anti-inflammatory, analgesic and antipyretic activities (Nimesulide) in seventy patients affected with a subacute or chronic rheumatic pathology. Nimesulide, given orally at a dosage of 200–600 mg daily for a mean duration of 26 days, induced either the resolution of the condition or a clinically useful improvement in 86% of the patients, with a low incidence of untoward side-effects characterized by a prevailing gastric localization.This publication has 3 references indexed in Scilit:
- The comparative gastric ulcerogenic activities of non-steroid anti-inflammatory drugsInflammation Research, 1977
- Mechanism of action of novel anti-inflammatory drugs diflumidone and R-805Biochemical Pharmacology, 1977