HAEMODYNAMIC RESPONSES TO ANTAGONISM OF TUBOCURARINE BLOCK WITH ATROPINE-NEOSTIGMINE MIXTURE IN CHILDREN
Open Access
- 1 September 1977
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 49 (9) , 901-905
- https://doi.org/10.1093/bja/49.9.901
Abstract
Following antagonsim of tubocurarine block with a mixture of atropine 20 μg/kg and neostigmine 50 μg/kg in 20 children, heart rate decreased from a control value of 110.4 beat/min to 90.1 at 5 min and 89.2 at 6 min (P−1. m−2 but a significant increase to 48 ml. beat−1.m−2 was observed at the 6th and 7th mins following the injection of the mixture (P<0.05). Cardiac index and mean arterial pressure remained unaltered throughout the period of observation. Normal sinus rhythm was maintained in all patients. It was concluded that antagonism of tubocurarine with an atropineneostigmine mixture does not produce any important haemodynamic change in children.This publication has 1 reference indexed in Scilit: