Contrast sensitivity dysfunction in Alzheimer's disease

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Abstract
We compared the spatial contrast sensitivity of six patients with mild to moderate Alzheimer9s disease (AD) and six age-matched control subjects in a parametric design. Results demonstrate reduced contrast sensitivity in patients with AD at all but the lowest frequency tested. The results suggest that the effect of AD on spatial contrast sensitivity is stronger at higher frequencies and provide a rationale for complaints of poor vision in AD patients.

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