The Disease Activity of Ulcerative Colitis and Crohn’s Disease

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Abstract
Talstad, I. & Gjone, E. The disease activity of ulcerative colitis and Crohn’s disease. Scand. J. Gastroent. 1976, 11, 403-408. The disease activity in ulcerative colitis and Crohn’s disease was studied. Parameters found to reflect the disease activity were given scores from 1 to 4. The score obtained by a patient compared with the maximum scores gives the percentage disease activity. The regressions between the percentage disease activity and the ESR in ulcerative colitis and Crohn’s disease were r=0.68 (p<0.001) and r = 0.48 (p<0.001), respectively. The different activity parameters have different time response curves explaining the occasional slight correlation. The percentage disease activity represents the mean activity of the different parameters at a given time. It is proposed to define slight, moderate, and severe ulcerative colitis or Crohn’s disease as percentage disease activity of 70 per cent, respectively.

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