Intermittent drug dosing intervals guided by the operational multiple dosing half lives for predictable plasma accumulation and fluctuation
- 16 April 2011
- journal article
- research article
- Published by Springer Nature in Journal of Pharmacokinetics and Pharmacodynamics
- Vol. 38 (3) , 369-383
- https://doi.org/10.1007/s10928-011-9198-0
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Rate and Extent of Drug Accumulation after Multiple Dosing RevisitedClinical Pharmacokinetics, 2010
- The Operational Multiple Dosing Half-life: A Key to Defining Drug Accumulation in Patients and to Designing Extended Release Dosage FormsPharmaceutical Research, 2008
- Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug researchTrends in Pharmacological Sciences, 2008
- Population Pharmacokinetic-Pharmacodynamic Modelling of Angiotensin Receptor Blockade in Healthy VolunteersClinical Pharmacokinetics, 2002
- Pharmacokinetics and pharmacodynamic effects of the angiotensin II antagonist valsartan at steady state in healthy, normotensive subjectsEuropean Journal of Clinical Pharmacology, 1997
- Pharmacokinetic-pharmacodynamic modelling as a tool to evaluate the clinical relevance of a drug-food interaction for a nisoldipine controlled-release dosage formEuropean Journal of Clinical Pharmacology, 1997
- A review of techniques for parameter sensitivity analysis of environmental modelsEnvironmental Monitoring and Assessment, 1994
- Plasma Concentration—Effect Relationships of Intravenous and Extended-Release Oral Felodipine in Hypertensive PatientsJournal of Cardiovascular Pharmacology, 1990
- Absolute Bioavailability and Effect of Food and Antacid on Diazepam Absorption from a Slow‐Release PreparationThe Journal of Clinical Pharmacology, 1984
- Disposition of sodium valproate in epileptic patients.British Journal of Clinical Pharmacology, 1978