Correlation of nonsense sites in the lacI gene with specific codons in the nucleotide sequence
- 1 August 1978
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 274 (5673) , 770-775
- https://doi.org/10.1038/274770a0
Abstract
Nonsense mutations derived from 90 different codons in the lacI gene of Escherichia coli were correlated with the I gene nucleotide sequence. In over 80 cases the specific codon which generates the nonsense mutation can be identified. The sequence shows that 14-16 sites arise through tandem double base changes.This publication has 17 references indexed in Scilit:
- Sequence of the lacI geneNature, 1978
- Biochemical characterization of lac repressor proteins produced by suppression of two amber mutationsJournal of Molecular Biology, 1977
- Genetic studies of the lac repressorJournal of Molecular Biology, 1977
- Genetic studies of the lac repressorJournal of Molecular Biology, 1977
- Identification of the UUG codon as a translational initiation codon in vivoJournal of Molecular Biology, 1975
- The Amino-Acid Sequence of lac RepressorProceedings of the National Academy of Sciences, 1973
- Translational Restarts: AUG Reinitiation of a lac Repressor FragmentProceedings of the National Academy of Sciences, 1972
- INFORMATIONAL SUPPRESSIONAnnual Review of Genetics, 1970
- Mutants that make more lac repressor.Proceedings of the National Academy of Sciences, 1968
- Base Composition of Nonsense Condons in E. coli: Evidence from Amino-Acid Substitutions at a Tryptophan Site in Alkaline PhosphataseNature, 1965