THE EFFECTS OF LEAD AND FIXATIVES ON ACTIVITY OF GLUTAMIC OXALACETIC TRANSAMINASE
- 1 March 1968
- journal article
- research article
- Published by SAGE Publications in Journal of Histochemistry & Cytochemistry
- Vol. 16 (3) , 181-184
- https://doi.org/10.1177/16.3.181
Abstract
Lead oxalacetate, a primary reaction product precipitate for the visualization of the activity of glutamic oxalacetic transaminase in tissue sections, is stable at a slightly alkaline pH. At concentrations which are used for tissue fixation a slight inhibitory effect on glutamic oxalacetic transaminase activity is produced by acetone while a glutaraldehyde-formaldehyde mixture results in marked reduction of activity. The concentration of lead which is used to form the primary reaction product does not significantly inhibit this enzyme activity.This publication has 2 references indexed in Scilit:
- Aldehyde as fixative for histochemical study of glutamic oxaloacetic transaminaseHistochemistry and Cell Biology, 1968
- THE EFFECT OF CATIONS ON THE DECARBOXYLATION OF OXALACETIC ACIDJournal of Biological Chemistry, 1949