Chronic obstructive pulmonary disease (COPD): Effects of bronchodilator drugs on normal and affected horses

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Abstract
The effects of the bronchodilator drugs, atropine, isoprenaline and terbutaline, on normal horses and on horses affected with chronic obstructive pulmonary disease (COPD), were assessed by pulmonary function tests and clinical examination. Normal horses were not affected but COPD horses responded by a marked decrease in intrathoracic pressure, a decrease in respiratory rate, an initial decrease followed by an increase in arterial O2 partial pressure and clinical improvement after treatment with all 3 drugs. The changes were temporary.