The hypermobility syndrome. Musculoskeletal complaints associated with generalized joint hypermobility.

Abstract
A reassessment was made of 24 patients with various musculoskeletal complaints and had generalized joint laxity; the latter possibly responsible for their complaints. The ranges of joint movement, body proportions, and metacarpal indices were measured and compared with other family members, rheumatic fever patients, and normal controls. Generalized familial joint laxity occurred in this group without any other features of hereditary connective tissue disorder. The wide range of associated symptoms is described. The hypermobility syndrome appears to predispose to the premature development of degenerative joint disease.

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