Plasmodium falciparum Gametocytes from Culture in Vitro Develop to Sporozoites That Are Infectious to Primates
- 10 September 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4564) , 1048-1050
- https://doi.org/10.1126/science.7051285
Abstract
Gametocytes of two strains of the human malaria parasite Plasmodium falciparum have been produced in high density by means of a continuous-flow cultivation system. The gametocytes of these two strains infected a mean of 36 percent and 71 percent, respectively, of Anopheles freeborni mosquitoes that fed on a suspension of red blood cells containing the cultured gametocytes. Sporozoites harvested from the infected mosquito salivary glands were infective to the chimpanzee ( Pan troglodytes ) and the owl monkey ( Aotus trivirgatus ).This publication has 12 references indexed in Scilit:
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