ALIMENTARY GLYCOSURIA IN THE RAT

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Abstract
This report represents a preliminary study of the ability of the rat to tolerate a force-fed high carbohydrate deit and of the amounts of glucose which were excretedin the urine when the assimilation limit was exceeded. Six male rats of the Sprague-Dawley strain were maintained on Purina Dog Chow until they reached a weight of 300 grams. They were then placed in metabolism cages and maintained on a fluid diet administered by stomach tube each morning (8:30 to 9:00 A.M.) and late afternoon (4:30 to 5:00 P.M.). The techniques and diet were modifications of those described by Reinecke, Ball and Samuels (1). The diet was made according to Table 1. The animals were brought to the normal feeding of 26 cc. per day on the fifth day. This level of food intake was continued for seven days and thereafter the amount was increased by 1 cc. per day per rat until the death of the animal.
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