SELECTION FOR LINKAGE MODIFICATION II. A RECOMBINATION BALANCE FOR NEUTRAL MODIFIERS
Open Access
- 1 August 1973
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 74 (4) , 713-726
- https://doi.org/10.1093/genetics/74.4.713
Abstract
A stable polymorphic equilibrium may be established at a selectively-neutral gene locus which controls the extent of recombination between two other selected loci. The condition for the existence of the stable polymorphism is analogous to heterozygous advantage. The heterozygote at the modifying locus should produce a recombination fraction allowing the greatest linkage disequilibrium. In the models treated this has the effect of producing the highest mean fitness. The relationship of these findings to general problems of coadaptation is discussed.Keywords
This publication has 3 references indexed in Scilit:
- The Evolutionary Development of Modifier GenesProceedings of the National Academy of Sciences, 1972
- Selection for linkage modification: I. Random mating populationsTheoretical Population Biology, 1972
- Linkage and selection: Two locus symmetric viability modelTheoretical Population Biology, 1970