Treatment of Salmonella Infections

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To the editor: In their article "The Risks of Endothelial Infection in Adults with Salmonella Bacteremia" in the December 1978 issue (1), Cohen and co-workers state that antibiotics may be indicated for treatment of acute salmonella gastroenteritis in patients older than age 50 to prevent complications of possible salmonella bacteremia. We are writing to discuss this suggestion and to seek clarification of several issues not completely addressed in the article. The patients in their 10 cases were all older than 50 years of age and had "evidence of infection" (presumably endothelial infection) before admission, and four of these 10 had

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