Reduced cellular cholesterol content in peroxisome-deficient fibroblasts is associated with impaired uptake of the patient's low density lipoprotein and with reduced cholesterol synthesis.

This publication has 25 references indexed in Scilit:

• The Role of Peroxisomes in Cholesterol Metabolism
  American Journal of Respiratory Cell and Molecular Biology, 1992
• Normal cholesterol synthesis in human cells requires functional peroxisomes
  Biochemical and Biophysical Research Communications, 1991
• Metabolism of acetyl-CoA by isolated peroxisomal fractions: formation of acetate and acetoacetyl-CoA.
  Journal of Lipid Research, 1991
• Rat liver peroxisomes catalyze the initial step in cholesterol synthesis. The condensation of acetyl-CoA units into acetoacetyl-CoA.
  Published by Elsevier ,1990
• Nonspecific lipid transfer protein (Sterol carrier protein-2) defective in patients with deficient peroxisomes.
  Cell Structure and Function, 1990
• Subcellular localization of sterol carrier protein-2 in rat hepatocytes: its primary localization to peroxisomes.
  The Journal of cell biology, 1989
• Infantile Refsum disease: an inherited peroxisomal disorder
  European Journal of Pediatrics, 1987
• 3-Hydroxy-3-methylglutaryl coenzyme A reductase localization in rat liver peroxisomes and microsomes of control and cholestyramine-treated animals: quantitative biochemical and immunoelectron microscopical analyses.
  The Journal of cell biology, 1986
• 3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells.
  Proceedings of the National Academy of Sciences, 1985
• Infantile phytanic acid storage disease, a possible variant of Refsum's disease: Three cases, including ultrastructural studies of the liver
  Journal of Inherited Metabolic Disease, 1982