Evaluation of Carboxymethylcellulose as an Injectable Carrier for Follicle Stimulating Hormone
- 1 February 1973
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Animal Science
- Vol. 36 (2) , 375-379
- https://doi.org/10.2527/jas1973.362375x
Abstract
Three experiments involving 330 immature female rats were conducted to compare physiological saline (PSS) and carboxymethylcellullose (CMC) as carriers for follicle stimulating hormone (FSH) and to evaluate quantitative relationships of FSH and CMC. One percent CMC as a carrier resulted in heavier ovarian and uterine weights than did the same quantity (0.5 mg) of FSH in PSS. This indicated an increase in the expressed biological activity of FSH. The apparent optimum ratio of FSH:CMC in the rat was 1 mg FSH to 2 ml or more of 1% CMC solution. There was also an indication that ovarian and uterine stimulation by FSH in PSS was less repeatable than FSH in CMC. Copyright © 1973. American Society of Animal Science . Copyright 1973 by American Society of Animal Science.Keywords
This publication has 1 reference indexed in Scilit:
- Dose-Response Relationships in Synchronized Beef Heifers treated with Follicle Stimulating HormoneJournal of Animal Science, 1969