CARBONIC ANHYDRASE IN THE PREMATURE

1 September 1968

journal article
Published by American Academy of Pediatrics (AAP) in Pediatrics

Vol. 42 (3) , 429-436
https://doi.org/10.1542/peds.42.3.429

Abstract

Carbonic anhydrase activity was measured in the blood of premature and full-term infants to determine if the arterial-alveolar carbon dioxide gradient was related to low levels of carbonic anhydrase. The time at which levels in these infants approached the adult was studied as well. The study demonstrates that CO₂ gradients do not correlate with blood carbonic anhydrase activity, and minimal or no activity can be associated with a small gradient. An increase in the carbonic anhydrase activity-produced by transfusion did not significantly change the CO₂ gradient. Premature infants approach adult levels of activity in 6 to 7 months.

Keywords

CARBONATE DEHYDRATASE

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