Spermidine in Regenerating Liver: Relation to Rapid Synthesis of Ribonucleic Acid
- 23 July 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 149 (3682) , 428-429
- https://doi.org/10.1126/science.149.3682.428
Abstract
The spermidine in rat liver increases after partial hepatectomy, and the rate of polyamine accumulation closely approximates the increased rate of synthesis of RNA in regenerating liver. The uptake by the liver of intravenously injected putrescine and the biosynthesis of spermidine are accelerated within 2 hours after the operation. The uptake of spermidine also increases during early regeneration.Keywords
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