Long-Term Survival after Advanced Neuroblastoma

Publisher Website
Google Scholar
Abstract
To the Editor: In 1984 we reported observing an improved response rate in patients with advanced neuroblastoma (Evans1 Stage III and IV), all of whom were more than one year of age at diagnosis, treated with either of two chemotherapy regimens: vincristine (Oncovin), cisplatin, teniposide (epipodophyllotoxin, or VM-26), and cyclophosphamide, with or without doxorubicin (Adriamycin).2 Of 42 consecutive patients, 6 had Stage III tumors and 34 had Stage IV disease. Overall, 31 (74 percent) had at least a "good partial" response including disappearance of all evidence of metastatic disease. Of the responders, 18 underwent one treatment and 7 underwent two . . .