Nanostructures via Noncovalent Synthesis: 144 Hydrogen Bonds Bring Together 27 Components

Abstract
This paper describes the spontaneous and reversible assembly of similar to 20 kDa synthetic hydrogen-bonded assemblies via the formation of 144 cooperative hydrogen bonds. These nanostructures (similar to3.0 x 5.5 nm), consisting of 27 different components, have been carefully characterized using a combination of H-1 NMR spectroscopy, MALDI-TOF MS using Ag+-labeling, gel permeation chromatography, and CD spectroscopy.