SEROLOGICAL PROPERTIES OF LIPOPOLYSACCHARIDE FROM STRAINS OF ORAL VEILLONELLA

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Abstract
Lipopolysaccharide (LPS) extracted with phenol‐water from five oral strains of Veillonella was studied by indirect haemagglutination techniques. The highly active LPS showed serological type‐specificity. LPS from at least two of the strains contained more than one anti‐genic determinant, carried by the same molecular complex. The determinant groups were of carbohydrate nature. Inhibition of haemagglutination with mono‐ and disaccharides gave information of the chemical composition of the determinant group in LPS from one of the strains examined. The LPS preparations were immunogenic in rabbits, giving rise to both ME‐resistant antibodies and antibodies sensitive to reductional cleavage with ME.