Leiomyosarcoma of the colon and rectum

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Abstract
Leiomyosarcoma of the colon is an uncommon lesion and may appear throughout the colon. Early diagnosis is seldom accomplished before complications such as bleeding or obstruction appear. Sometimes it is histologically difficult to distinguish between a benign and a malignant leiomyoma. Some leiomyomas have biologic evidence of malignancy. Five [human] cases of leiomyosarcoma are described, 1 of which was histologically diagnosed as a leiomyoma, but 2 yr later, at laparotomy, metastases were found.

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