Effect of Furosemide on Renal Medullary Sodium Gradient.
- 1 February 1965
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 118 (2) , 372-374
- https://doi.org/10.3181/00379727-118-29846
Abstract
Summary Furosemide, 25 mg/kg/hr (25 mg/kg prime) abolished the sodium medullary gradient in the dog kidney. It is concluded that the natruresis produced by furosemide is due, at least in part, to inhibition of sodium reabsorption in the ascending limb of the loop of Henle.Keywords
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