Lithium Iodide in the Treatment of Confusional States

Abstract
Lithium iodide was administered intravenously to 15 patients and neuroleptic medication was administered to another matched 15 patients. The patients in both groups had been diagnosed as suffering from confusional psychosis. The results were tested by a sequential analysis method. Lithium proved the better drug in only two pairs of the series. In 13 pairs (87 per cent.) the neuroleptic drug gave a better result (p<0.1). In nine of these cases lithium did not prove useful at all and in four cases only could a slight sedative effect be observed. The results of the investigation support Strömgren's view that lithium therapy is chiefly limited to the sphere of affective psychoses.

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