Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas
- 3 January 2005
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (1) , 25-28
- https://doi.org/10.1016/j.bmcl.2004.10.044
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- Unraveling the Chemistry of Chemokine Receptor LigandsChemical Reviews, 2003
- Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitorsBioorganic & Medicinal Chemistry, 2003
- Biological evaluation and interconversion studies of rotamers of SCH 351125, an orally bioavailable CCR5 antagonistBioorganic & Medicinal Chemistry Letters, 2003
- Chemokines, chemokine receptors and small-molecule antagonists: recent developmentsTrends in Pharmacological Sciences, 2002
- CC chemokine receptor 5 and renal-transplant survivalThe Lancet, 2001
- Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the IntestineThe Journal of Immunology, 2000
- CCR5 Δ32, matrix metalloproteinase-9 and disease activity in multiple sclerosisJournal of Neuroimmunology, 2000
- An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.Proceedings of the National Academy of Sciences, 1996