Retinosomes
Open Access
- 16 August 2004
- journal article
- review article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 166 (4) , 447-453
- https://doi.org/10.1083/jcb.200405110
Abstract
Lipid bodies form autonomous intracellular structures in many model cells and in some cells of specific tissue origin. They contain hydrophobic substances, a set of structural proteins such as perilipin or adipose differentiation-related protein, enzymes implicated in lipid metabolism, and proteins that participate in signaling and membrane trafficking. Retinosomes, particles reminiscent of lipid bodies, have been identified in retinal pigment epithelium as distinct structures compartmentalizing a metabolic intermediate involved in regeneration of the visual chromophore. These observations suggest that lipid bodies, including retinosomes, carry out specific functions that go beyond those of mere lipid storage organelles.Keywords
This publication has 52 references indexed in Scilit:
- Lipids partition caveolin‐1 from ER membranes into lipid droplets: updating the model of lipid droplet biogenesisThe FASEB Journal, 2004
- Lecithin-retinol Acyltransferase Is Essential for Accumulation of All-trans-Retinyl Esters in the Eye and in the LiverJournal of Biological Chemistry, 2004
- Noninvasive two-photon imaging reveals retinyl ester storage structures in the eyeThe Journal of cell biology, 2004
- Role of the hydrophobic domain in targeting caveolin-1 to lipid dropletsThe Journal of cell biology, 2004
- Rpe65 Is a Retinyl Ester Binding Protein That Presents Insoluble Substrate to the Isomerase in Retinal Pigment Epithelial CellsPublished by Elsevier ,2004
- Functional Interaction between the Two Halves of the Photoreceptor-specific ATP Binding Cassette Protein ABCR (ABCA4)Published by Elsevier ,2003
- LipolysisThe Journal of cell biology, 2003
- Methods Issue on Nuclear Structure and ChromatinMethods, 1999
- Polyenes and visionChemistry & Biology, 1996
- Induction of the Adipose Differentiation-Related Protein in Liver of Etomoxir-Treated RatsBiochemical and Biophysical Research Communications, 1996